Morphogenesis of vascular networks in living systems Two examples :
the chicken-embryo yolk sac and the jellyfish Aurelia aurita
Annemiek J.M. Cornelissen
Laboratoire Matière et Systèmes Complexes
CNRS & Université Paris Diderot
Morphogenesis of living systems is controlled by a complex of processes in which also mechanical forces play a role. Mechanical forces can contribute either on a cellular scale by impacting on the signaling pathways, or on a tissue scale affecting the cell movements and deformations (compression, extension, intercalation, and rearrangement etc). In my research I aim to understand how mechanical self-organized processes are involved in the morphogenesis of vascular network structures. I will present two animal models, the jellyfish Aurelia aurita and the chicken embryo yolk-sac in which we challenge the hypothesis that tissue growth induces mechanical constraints that are implicated in governing the pattern of their vascular network.